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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK9
All Species:
35.76
Human Site:
T87
Identified Species:
52.44
UniProt:
P50750
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50750
NP_001252.1
372
42778
T87
N
L
I
E
I
C
R
T
K
A
S
P
Y
N
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094502
352
40482
P71
I
C
R
T
K
A
S
P
Y
N
R
C
K
G
S
Dog
Lupus familis
XP_548446
534
59045
T249
N
L
I
E
I
C
R
T
K
A
S
P
Y
N
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_570930
372
42743
T87
N
L
I
E
I
C
R
T
K
A
S
P
Y
N
R
Rat
Rattus norvegicus
Q641Z4
372
42743
T87
N
L
I
E
I
C
R
T
K
A
S
P
Y
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520593
314
36161
C48
I
Y
L
V
F
D
F
C
E
H
D
L
A
G
L
Chicken
Gallus gallus
Q5ZKN1
372
42784
T87
N
L
I
E
I
C
R
T
K
A
S
P
Y
N
R
Frog
Xenopus laevis
Q4V862
376
43205
P91
I
C
R
T
K
V
S
P
T
A
N
Q
Y
N
R
Zebra Danio
Brachydanio rerio
NP_997756
393
45129
T108
N
L
I
E
I
C
R
T
K
A
T
Q
F
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477226
404
46768
T119
N
L
I
E
I
C
R
T
K
A
T
A
T
N
G
Honey Bee
Apis mellifera
XP_396015
382
43973
T93
N
L
I
E
I
C
R
T
K
A
T
Q
Y
N
R
Nematode Worm
Caenorhab. elegans
Q9TVL3
478
53575
S155
I
E
V
C
S
A
K
S
T
G
T
T
G
S
K
Sea Urchin
Strong. purpuratus
XP_798269
410
46418
T116
P
L
Y
E
I
C
R
T
K
A
T
A
Y
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
Q102
P
G
R
D
R
D
D
Q
G
K
P
D
N
N
K
Baker's Yeast
Sacchar. cerevisiae
P23293
657
74221
I133
V
Y
D
H
S
P
D
I
T
N
A
A
S
S
N
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
H95
L
E
E
M
A
I
E
H
P
P
R
T
D
K
R
Conservation
Percent
Protein Identity:
100
N.A.
92.4
68.5
N.A.
98.6
98.6
N.A.
77.9
93
89.3
85.5
N.A.
66
72.7
43.3
67.3
Protein Similarity:
100
N.A.
93.5
69.4
N.A.
99.7
99.7
N.A.
80.3
95.4
94.1
89.5
N.A.
75.9
83.2
56.4
75.8
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
0
100
26.6
80
N.A.
73.3
86.6
0
73.3
P-Site Similarity:
100
N.A.
0
100
N.A.
100
100
N.A.
13.3
100
33.3
93.3
N.A.
80
93.3
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
25.2
31.7
Protein Similarity:
N.A.
N.A.
N.A.
51
39.4
45.6
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
13
0
0
0
63
7
19
7
0
0
% A
% Cys:
0
13
0
7
0
57
0
7
0
0
0
7
0
0
0
% C
% Asp:
0
0
7
7
0
13
13
0
0
0
7
7
7
0
0
% D
% Glu:
0
13
7
57
0
0
7
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
7
7
0
0
7
13
7
% G
% His:
0
0
0
7
0
0
0
7
0
7
0
0
0
0
0
% H
% Ile:
25
0
50
0
57
7
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
7
0
57
7
0
0
7
7
13
% K
% Leu:
7
57
7
0
0
0
0
0
0
0
0
7
0
0
7
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
0
0
13
7
0
7
69
7
% N
% Pro:
13
0
0
0
0
7
0
13
7
7
7
32
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
19
0
0
0
% Q
% Arg:
0
0
19
0
7
0
57
0
0
0
13
0
0
0
63
% R
% Ser:
0
0
0
0
13
0
13
7
0
0
32
0
7
13
7
% S
% Thr:
0
0
0
13
0
0
0
57
19
0
32
13
7
0
0
% T
% Val:
7
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
7
0
0
0
0
0
7
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _